Florian Wildschek

Ease of scale-up of coating processes by using Kollicoat IR grades.

Dr. Florian Wildschek, Technical service manager, BASF, Germany

In most cases coating polymers cannot be used alone in solid oral dosage forms but have to be used with other additives. As it is much easier to handle just one mixture of polymers and additives, there is a clear trend towards so-called coating systems. The basis of the new coating system Kollicoat IR White is Kollicoat IR, which is a graft copolymer consisting of 75% polyvinyl alcohol units and 25% polyethylene glycol units. Kollicoat IR shows superior mechanical properties and a low viscosity compared to competetive products. Therefore, scale-up processes during the transfer from lab scale to production batches are very easy using this innovative polymer for instant release coatings.

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